Catalyst Ligands

Many of the tertiary phosphines sold as catalyst ligands are of a proprietary nature and are developed with the customer for one particular application. However, Cytec does offer "off the shelf" ligands under the CYTOP^® organophosphine trade name such as CYTOP 355 - tricyclopentylphosphine and CYTOP 341 - triisobutylphosphine. The former is a potential alternate to tricyclohexylphosphine in the "Grubbs" catalyst. In addition, Cytec also offers several unique primary and secondary alkylphosphines such as CYTOP 266 - dicyclohexylphosphine, CYTOP 255 - dicyclopentylphosphine, CYTOP 241 - diisobutylphosphine, CYTOP 220 - dinorbornylphosphine and CYTOP 216 - 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phosphaadamantane. The 6-phenyl analogue of the latter is particularly effective as a ligand for Suzuki cross-coupling reactions. Such primary and secondary phosphines are useful intermediates for the synthesis of catalyst ligands.

Cytec's triarylphosphines (TOTP) and bidentate ligands (DPPB) have been used in a variety of catalytic applications in industrial and pharmaceutical industries. While both have application as hydroformylation catalyst ligands, they also find use in carbonylations, catalytic Heck and Suzuki couplings.